(a) The sporozoites enter in human blood due to Female Anopheles biting.
(b) When the female Anopheles sucks the blood of an infected human host, it receives RBCs containing different stages of the erythrocytic cycle. In mosquito stomach, male gametes divide to form microgametes. Female gametes mature and called macrogametes. The fertilization takes place and forms zygote.
(c) The parasite multiplies within the RBCs and ruptures the cells. Symptoms include a headache, chill, shivering, nausea, muscular pain and recurring fever every 3rd and 4th day. The patient displays syn.rptoms of malaria even after a period of 14 days from infection. This time of interval is known as the incubation period, in which the parasite multiplies to increase its number so that it can produce enough toxins, which cause the periodic recurrence of chill and high fever during malaria.
The Lifecycle of Plasmodium vivaxin man and the mosquito.
Life Cycle of Malarial Parasite.