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Answer the following questions: 

A. Explain sex determination in humans.

B. How do human males with ‘XXY’ abnormality suffer ?

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Sex Determination in Humans 

* Humans show XY type of sex determining mechanism. 

* Out of 23 pair of chromosomes, 22 are autosomes (same in both males and females). 

* Females have a pair of X-chromosomes. 

* Males have an X and a Y chromosome. 

* During spermatogenesis males produce two types of gametes with equal probability – sperm carrying either X or Y chromosome. 

* During oogenesis females produce only one types of gamete – having X chromosome. 

* An ovum fertilised by the sperm carrying X-chromosome develops into a female (XX) and an ovum fertilised by the sperm carrying Y-chromosome develops into a male (XY).

B. The XXY individual suffers from Klinefelter’s syndrome.

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