HIV virus gains entry into Macrophages and (Helper) T-lymphocytes after getting into the human body.
Events that occur in the cells are:
i. Viral RNA forms DNA by reverse transcription using the enzymes reverse transcriptase and directs the infected cells to produce viral particles.
ii. Macrophages continue to produce viral particles and function as HIV factories.
iii. The viral particles simultaneously enters into helper T-lymphocytes, replicates and produce viral progenies.
iv. The number of T-lymphocytes progressively decreases in the body of the infected person.
v. During this person suffers from bouts of fever, weight loss. Also decrease in the number of cells leads to weakening of immune system.
