Question

Complete the equation for reductive amination ......... .
`+NH_(4)^(+)+NADPH overset(?)rarr "glutamate" + H_(2)O + NADP`

Answer 1

Reductive Amination Ammonia combines with a keto acid (like `alpha`-ketoglutaric acid or oxaloacetic acid) to form amino acid in presence of a reduced coenzyme (NADH, NADPH) and enzyme dehydrogenase (e.g., glutamate dehydrogenase, aspartate dehydrogenase).
`alpha`- ketoglutaric acid `+ NH_(4)^(+) + NAD (P) H underset("dehydrogenase")overset("Glutamate")rarr "Glutamate" + H_(2)O + NAD (P)`
Oxaloacetic acid `+ NH_(4)^(+) + NAD (P) H underset("dehydrogenase") overset ("Aspartate") rarr "Asparatate" + H_(2)O + NAD (P)`