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Which is true about the difference between cortical and juxtamedullary nephrons?
A. Most nephrons are juxtamedullary.
B. The efferent arterioles of cortical nephrons give rise to most of the vasa recta
C. The afferent arterioles of the juxtamedullary nephrons give rise to most of the vasa recta.
D. Juxtamedullary nephrons generate a hyperosmotic medullary interstitium.

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Correct Answer - D
Cortical nephrons either have short or do not have loops of Henle. Only juxtamedullary nephrons have long loops of Henle, which plunge into the renal medulla and create a hypersomotic interstitium via counter current multiphication.

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