1. Capacitation is the process by which the sperms are made capable to swim up to the fallopian tubes. This process takes place in 5-6 hours.
2. 50% of ejaculated sperms die due to unfavourable vaginal and uterine conditions.
3. The remaining sperms are capacitated with the help of prostaglandin and vestibular secretions of female tract. It involves the changes in the membrane covering the acrosome.
4. Due to capacitation, acrosome membrane becomes thin, Calcium ions enters the sperm and their tail begin to show rapid whiplash movements.
5. Sperms become extra active and then they ascend upwards to reach fallopian tubes
6. After capacitation the sperms swim through the vagina and uterus and reach ampulla of fallopian tube within 5 minutes.
