A third group is least likely to enter between two groups in the mta relationship. This is the result of steric hindrance and increases in importance with the size of the groups on the ring and with the size of the attaching species. When a meta-directing group is meta to an ortho-para directing group, the incoming group primarily goes ortho to the meta directing group rather than para.
Q.
A.
B.
C.
D. Both (A) and (B)
