Question

The principal nitrogenous excretory compound in humans is synthesised

(a) in kidneys but eliminated mostly through liver

(b) in kidneys as well as eliminated by kidneys

(c) in liver and also eliminated b,v the same through bile

(d) in the liver but eliminated mostly through kidneys

Answer 1

Correct Option (d) in the liver but eliminated mostly through kidneys
Explanation:

In humans, the principal nitrogenous excretory compound (i.e. urea) is synthesised in liver by Ornithine cycle and is eliminated mostly through kidney as nitrogeneous excretory product in liver, one molecule of CO₂ is activated by biotin and combines with two molecules of NH₃ in the presence of carbamyl phosphate synthetase enzyme and 2ATP to form carbamyl phosphate and one molecule of H₂O is released.

Carbamyl phosphate reacts with Ornithine and forms Citrulline. Citrulline combines with another molecule of ammonia and form arginine that is broken into urea and Ornithine in the presence of an enzyme arginase and water.

Answer 2

I think it is option (d)