The following reactions cannot be explained by the open chain structure of D-glucose .
`to` Glucose has aldehyde group, but it does not respond to the reagents like schiffs reagent, `NaHSO_3. NH_3` etc.
`to` The penta acetyl derivative of glucose doesnot react with hydroxyl amine.
`to alpha " and " beta` - methyl glucosides cannot be explained by its open chain structure.