When a vaccine is introduced, it induces the production of antibodies in the body against the antigens of the disease. These antibodies neutralise the antigens at the time of actual infection. They also cause the productionof B and T cells which recognize the pathogen quickly on subsequent exposure.
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Tetanus is caused by a deadly bacterium which require quick response to neutralise. Therefore, preformed antitoxin is administrated to neutralise the effect of the bacterial toxin.