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Explain heterocrine nature of pancreas with the help of histological structure.

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Pancreas: 

1. Pancreas is a leaf shaped heterocrine gland present in the gap formed by bend of duodenum under the stomach. 

2. Exocrine part of pancreas is made up of acini, the acinar cells secrete alkaline pancreatic juice that contains various digestive enzymes. 

3. Pancreatic juice is collected and carried to duodenum by pancreatic duct.

4. The common bile duct joins pancreatic duct to form hepato-pancreatic duct. It opens into duodenum. 

5. Opening of hepato-pancreatic duct is guarded by sphincter of Oddi.

6. Endocrine part of pancreas is made up of islets of Langerhans situated between the acini. 

7. It contains three types of cells a-cells which secrete glucagon, P-cells which secretes insulin and 5 cells secrete somatostatin hormone.

8. Glucagon and insulin together control the blood-sugar level. 

9. Somatostatin hormone inhibits glucagon and insulin secretion.

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