Read the given paragraph and select the option that correctly fills the blanks in it. Hormones produce their effect on target tissue by binding to specific A called hormone receptors located in the target tissues only water soluble hormones usually need B receptor that generate C messenger for regulating through cell membrane and bind to E receptors, mostly nuclear receptors. The hormone receptor complex enter the nucleus and moslty regulate gene expression or chromosome function by interaction of hormone receptor complex with the genone.
A. `{:(A,B,C,D,E),("proteins","membrane-bound","second","lipid","Intracellular"):}`
B. `{:(A,B,C,D,E),("lipids","membrane-bound","second","water","intracellular"):}`
C. `{:(A,B,C,D,E),("proteins","intracellular","second","lipid","extracellular"):}`
D. `{:(A,B,C,D,E),("proteins","membrane","primary","lipid","intracellular"):}`
