Question

If the selected window size is too long, sensitivity of the alignment is lost.

(a) True

(b) False

I got this question in an online quiz.

I want to ask this question from Methods in portion Pairwise Sequence Alignment of Bioinformatics

Answer 1

The correct answer is (a) True

Easy explanation: Dots are only placed when a stretch of residues equal to the window size from one sequence matches completely with a stretch of another sequence. This method has been shown to be effective in reducing the noise level. The window is also called a tuple, the size of which can be manipulated so that a clear pattern of sequence match can be plotted. However, if the selected window size is too long, sensitivity of the alignment is lost.