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Which of the following catalyzes ADP-ribosylation of a diphthamide residue?

(a) Chloramphenicol

(b) Cycloheximide

(c) Diphtheria toxin

(d) Ricin

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The correct option is (c) Diphtheria toxin

For explanation I would say: Diphtheria toxin catalyzes ADP-ribosylation of a diphthamide residue of eukaryotic elongation factor eEF2, thereby inactivating it.

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