Question

When the two domains are located in two different proteins, to preserve the same functionality, their close proximity and interaction have to be preserved as well.

(a) True

(b) False

The question was posed to me by my school principal while I was bunking the class.

The origin of the question is Protein Interactions in division Functional Genomics & Proteomics of Bioinformatics

Answer 1

Right answer is (a) True

The best explanation: In this method, by studying gene/protein fusion events, protein–protein interactions can be predicted. This prediction rule has been proven to be rather reliable and since successfully applied to a large number of proteins from both prokaryote and eukaryotes.