Question

The classical substances that increases the sensitivity of pain receptors by enhancing the pain-provoking effect of bradykinin is
1. Nociceptor
2. Endorphins
3. Encephalin
4. Prostaglandins
5.

Answer 1

Correct Answer - Option 4 : Prostaglandins

Concept:-

• The classical substance that increases the sensitivity of pain receptors by enhancing the pain-provoking effect of bradykinin is prostaglandins.
• Prostaglandins increase the sensitivity of nerve terminals to bradykinin and other pain-producing substances.
• Bradykinin causes pain by directly stimulating primary sensory neurons and stimulating the release of substance P, neurokinin, and calcitonin gene-related peptides.

• Nociceptive is a type of pain that occurs due to damage to body tissues. Nociceptive pain feels like a sharp, aching, or throbbing. A nociceptor is a sensor of the pain pathway.
• Endorphins are the body's natural pain relievers. They are produced and stored in the pituitary gland. The function of endorphins is to inhibit the transmission of pain signals.
• Encephalin is an alternative form of enkephalin.