Question

DNA dependent RNA polymerase catalyzes the polymerisation in which direction____.
1. Unidirectional 5 to 3
2. Unidirectional 3 to 5
3. Bidirectional 5 to 3 and 3 to 5
4. Bidirectional 3 to 5 and 5 to 3

Answer 1

Correct Answer - Option 1 : Unidirectional 5 to 3

The correct answer is Unidirectional 5 to 3.

• The two strands have opposite polarity and the DNA-dependent RNA polymerase also catalyze the polymerization in only one direction, that is, 5 to 3,
• The strand that has the polarity 3 to 5 acts as a template, and it is also referred to as a template strand.
• The other strand which has the polarity 5 to 3 and the sequence same as RNA is displaced during transcription.

So, the correct answer is 'Only 5 to 3'.