The three difficulties that the Europeans faced in reaching the interior parts of Africa are:
1. Besides attempting to build their colonies in Africa, the Europeans continued to explore the interior of the continent.
2. They travelled to the source of the Nile in the north.
3. In the west, they explored the entire valley of the Niger and in the south, they moved northwards from Cape Town.
4. There they explored the region around the river Zambezi.