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How can we use LEU 2 gene as a selectable marker?

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How can we use LEU 2 gene as a selectable marker?

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The LEU2 gene codes for an enzyme which is needed for the synthesis of the amino acid leucine. Yeast cells having this plasmid can grow on a medium lacking leucine and hence can be selected over cells not containing the plasmid.

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How can LEU 2 gene be used as a selectable marker?
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