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Which amino acid is substituted in sickle cell anamia ?

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Which amino acid is substituted in sickle cell anamia ?
A. Gutamic acid by valine in `alpha`-chain
B. Glutamic acid by valine in `beta`-chain
C. Valine by glutamic acid in `beta`-chain
D. Valine by glutamic acid in `alpha`-chain
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Correct Answer - B
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