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Define cardiac output. How can it be calculated?

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The amount of blood pumped out by each ventricle per minute is called cardiac output(CO).

It is a product of heart rate (HR) and stroke volume (SV). Heart rate or pulse is the number of beats per minute.

Pulse pressure = systolic pressure – diastolic pressure.
Stroke volume (SV) is the volume of blood pumped out by one ventricle with each beat. SV depends on ventricular contraction.

CO = HR x SV

SV represents the difference between EDV (amount of blood that collects in a ventricle during diastole) and ESV (volume of blood remaining in the ventricle after contraction).

SV = EDV – ESV

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