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What are the Factors affecting stability of conformations?

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(I) Angle strain : Any deviation from "normal" bond angles are accompanied by angle strain. It is normally present in the cyclic structures but absent in the acyclic structures. 

(II) Torsional strain : Any pair of tetrahedral carbons attached to each other tend to have their bonds staggered for minimum repulsion between their bonds. Any deviation from the staggered conformation are accompanied by torsional strain. It is also known as Pitzer strain or Eclipsing strain. 

(III) van der Waals strain : Non bonded atoms or groups that just touch each other i.e. they are about as far apart as the sum of their van der Waals radii, if brought any closer together they repel each other. Such crowding together is accompanied by van der Waals strain.

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