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Which one of the following factors will not affect the Hardy-Weinberg equilibrium? 

(1) Genetic recombination 

(2) Genetic drift 

(3) Gene migration 

(4) Constant gene pool

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Correct option is (4) Constant gene pool

As a constant gene pool will not disturb the Hardy-Weinberg equilibrium. 

Option (1), (2) & (3) will affect the equilibrium leading to evolution.

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