A Down’s syndrome I 11th chormosome B α-Thalassemia II ‘X’ chromosome C β-Thalassemia III 21st chromosome D Klinefelter’s syndrome IV 16th chromosome

Question

Match List I with List II

	List I		List II
A	Down’s syndrome	I	11th chormosome
B	α-Thalassemia	II	‘X’ chromosome
C	β-Thalassemia	III	21st chromosome
D	Klinefelter’s syndrome	IV	16th chromosome

Choose the correct answer from the options given below :

(1) A-I, B-II, C-III, D-IV

(2) A-II, B-III, C-IV, D-I

(3) A-III, B-IV, C-I, D-II

(4) A-IV, B-I, C-II, D-III

Answer 1

Correct option is (3) A-III, B-IV, C-I, D-II

Down’s syndrome is due to presence of an additional copy of chromosome number 21. Klinefelter’s syndrome is caused due to presence of an additional copy of X-chromosome. \(\alpha\)-Thalassemia is controlled by two closely linked genes on chromosome 16 of each parent. \(\beta\)-Thalassemia is controlled by a single gene HBB on chromosome 11 of each parent.