You can configure health checks for a Target Group using the AWS Management Console, AWS CLI, or AWS SDK. Here's an example using AWS CLI:
aws elbv2 modify-target-group --target-group-arn arn:aws:elasticloadbalancing:region:account-id:targetgroup/my-targets/12345 --health-check-protocol HTTP --health-check-port 80 --health-check-path /health --interval-seconds 30 --timeout-seconds 5 --healthy-threshold-count 5 --unhealthy-threshold-count 2