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How do cells of neoplastic tumors obtain oxygen and nutrients and release wastes?

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In neoplastic tumors a phenomenon called angiogenesis occurs. Angiogenesis is the formation of new blood vessels. Neoplastic cells induce the formation of new blood vessels to irrigate and drain the neoplastic tissue. Angiogenesis is important because the tumor growth depends on it. A lot of research on cancer has tried to discover  natural and synthetic substances to inhibit angiogenesis.

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