• The malarial parasite (Plasmodium) requires two hosts–human and mosquitoes to complete its life cycle; the female Anopheles mosquito is the vector (transmitting agent) too.
• Plasmodium enters the human body as sporozoites through the bite of infected female Anopheles mosquito.
• The parasites initially multiply within the liver cells and then attack the red blood cells resulting in their rupture to release haemozoin, which is responsible for chill and high fever recurring every three to four days.
• When a female Anopheles bites an infected person, these parasites (gametocytes) enter the mosquito’s body, perform multiplication within them to form sporozoites.
• Sporozoites are stored in salivary glands of mosquito and infect humans during biting.
