Question

Explain the following giving one example for each:
(i) Reimer–Tiemann reaction.
(ii) Friedel–Crafts acetylation of anisole.

Answer 1

(i) Reimer–Tiemann Reaction: Treatment of phenol with chloroform in the presence of aqueous alkali at 340 K followed by hydrolysis of resulting product gives salicylaldehyde as a major product.

(ii) Friedel–Crafts acylation of anisole: Anisole on treatment with acylchloride in the presence of anhydrous AlCl₃ undergo electrophilic substitution in the ring at ortho and para positions. For example,