The tangent at (a cos θ, b sin θ) to the ellipse is
x/a cosθ + y/b sin θ = 1
This meets the axes at the points A(a sec θ , 0) and B(0, b cosec θ). Let (x1, y1) be the midpoint of (bar)AB. Therefore

Therefore, the locus of (x1, x2) is
a2/x2 + b2/y2 = 4