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Haemoglobin is a Fe containing protein responsible for oxygen transport in the blood. The curves given below indicate the percentage saturation of haemoglobin by O2 as a function of partial pressure of O2.

Which of the following statement/s is /are correct for the given curves? 

I. In presence of CO2, higher O2 P is needed for a given percentage saturation 

II. In presence of CO2, lower O2 P is needed for a given percentage saturation 

III. The maximum percentage saturation is not affected by the presence of CO2 

IV. In the absence of CO2, maximum saturation of haemoglobin occurs at lower PO2

(A) I and IV 

(B) II and IV 

(C) I, III and IV 

(D) II and III

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Best answer

Correct answer is (C) I, III and IV

According to given information graph I would be in presence of CO2 and II would be in absence of CO2

Now we can conclude from graph that 

(i) In presence of CO2 higher O2 P in needed for a given percentage saturation. 

(ii) The maximum percentage saturation is not affected by presence of CO2

(ii) In the absence of CO2, maximum saturation of haemoglobin occurs at lower O2.

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