Let’s take P(x , y) be any point on the curve and AB be the tangent to the given curve at P.
Also given, P is the mid-point of AB
So, the coordinates of A and B are (2x, 0) and (0, 2y) respectively.

The slope of the tangent AB = (2y – 0)/ (0 – 2x) = -y/x

Thus, the required equation is xy = 1