(i) It is regulated by a ‘limit-control feedback’ or ‘push and pull feedback' mechanism.
(ii) When sugar level in blood increases, insulin is secreted and glucagon secretion is inhibited.
(iii) When blood-sugar level falls, for instance during excessive physical labour or stress, secretion of glucogen is stimulated and insulin secretion is inhibited.
(iv) This is the self-regulating device.