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Explain the mode of infection and cause of elephantiasis.

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Mode of infection, i.e. transmission:

1. The parasite Wuchereria bancrofti is transmitted from a patient to other normal human being by female Culex mosquito. 

2. The filarial larvae leave mosquito body and arrive on the human skin where they penetrate the skin and enter inside. 

3. They undergo two moultings to become adults. Later they settle in the lymphatic system. They incubate for about 8-16 months. 

4. When they settle in lymphatic system, this infection is called lymphatic filariasis. 

5. The worms start infecting lymphatic circulation resulting into enlargement of lymph vessels and lymph nodes. The extremities like legs or limbs become swollen which resembles elephant legs. Therefore it is called elephantiasis. 

6. This condition is lymphoedema, i.e. accumulation of lymph fluid in tissue causing swelling.

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