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The global sequence alignment is suitable when the two sequences are of dissimilar length, with a negligible degree of similarity throughout.

(a) True

(b) False

I got this question during an internship interview.

The origin of the question is Needleman topic in division Multiple Sequence Alignment of Bioinformatics

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Correct choice is (b) False

For explanation I would say: The global sequence alignment is suitable when the two sequences are of similar length, with a significant degree of similarity throughout. It gives the best alignment over the entire length of two sequences.

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