Question

Once the proteins are translocated within the organelles, protease cleavage takes place to remove the signal sequences and generate mature proteins.

(a) True

(b) False

The question was posed to me in semester exam.

This is a very interesting question from Protein Sorting in portion Functional Genomics & Proteomics of Bioinformatics

Answer 1

The correct option is (a) True

The explanation is: It is an example of posttranslational modification. Even in prokaryotes, proteins can be targeted to the inner or outer membranes, the periplasmic space between these membranes, or the extracellular space. The sorting of these proteins is similar to that in eukaryotes and relies on the presence of signal peptides.