Question

Trypsin hydrolyses a peptide bond on the carboxyl side of
1. Leucine
2. Phenylalanine
3. Arginine
4. Proline

Answer 1

Correct Answer - Option 3 : Arginine

Trypsin hydrolyses a peptide bond on the carboxyl side of Arginine.

• Trypsin is formed in the small intestine when its proenzyme form, the trypsinogen produced by the pancreas, is activated. 
• It hydrolyses a peptide bond on the carboxyl side of Arginine.

•  Leucine
  • Leucine is an α-amino acid, meaning it contains an α-amino group, an α-carboxylic acid group, and a side chain isobutyl group, making it a non-polar aliphatic amino acid.​
  • Eggs, sesame seeds, pumpkin seeds are rich in leucine.
• Phenylalanine
  • ​Phenylalanine is an essential aromatic amino acid and is a precursor of melanin, dopamine, noradrenalin, and thyroxine
• Proline
  • ​Proline is often found at the end of α helix or in turns or loops.
  • Unlike other amino acids which exist almost exclusively in the trans- form in polypeptides, proline can exist in the cis-configuration in peptides